Sensitivity to fat in dyspepsia

This work unlined the importance of fat in generating dyspeptic symptoms by demonstrating how duodenal infusions of fat could sensitise the stomach to distension and to motion sickness. These effects could be treated by drugs that acted on cholecystokinin, opiate and serotonin receptors. Khan, M.I., Read, N.W., Grundy, D. (1993)... Read more »

A method for measuring the activity of the gastropyloroduodenal unit in man

Dr John Dent from the University of Adelaide had invented the perfused sleeve catheter for measuring the pressures across a mobile sphincter. He incorporated this into a multilumen catheter assembly for recording the contractile activity in the stomach, pylorus and duodenum in human subjects. My experience with measuring transmucosal potential... Read more »