From 1972 to 2002, I worked as a clinical scientist investigating the factors that influenced gastrointestinal function and how they might be relevant to the kind of illnesses I saw frequently in my gastroenterology clinic. These included irritable bowel syndrome, coeliac disease, chronic constipation, dyspepsia and faecal incontinence.

I enjoyed medical research. It appealed to the explorer in me. It was a wonderful privilege to have the opportunity to observe new phenomena, conceive new ideas and to discuss and develop them with others.

In collaboration with colleagues both in the UK and in the United States and Australia and assisted by over 50 research students, we published over 500 scientific papers and review articles, covering a wide variety of different topics associated with the gut. The following contains an outline of our findings in each category and a sample of published papers.